The flight of fight response is a very important response, right? Evolutionarily, it's protected our species. And we need it to be able to walk down. Once you get out of danger, your metabolic system goes back to normal. But in the modern world, because our guts are so messed up, when cordisaw dumps into the gut, it actually makes the super-leaky compound called cortisa that increases leaky gut. We're talking about in minutes, not hours or days as some people think.