Adverse Childhood Experiences - HPA axis & Brain changes: cortisol, amygdala, hippocampus, cytokines, & epigenetics (Part 3 of ACE series)
Psychiatry & Psychotherapy Podcast
Exploring the Role of FKBP5 in Cortisol Regulation and its Link to Mental Health Disorders
This chapter provides an in-depth analysis of how the FKBP5 protein affects cortisol binding, gene transcription, and its relevance in mental health conditions like PTSD. It also discusses the role of specific gene polymorphisms, FKBP5 expression, glucocorticoid receptor sensitivity, and epigenetic changes due to childhood maltreatment.
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