In this episode, Dr. Jockers and Dr. William Hsu dive into how nourished fasting can reduce insulin resistance, activate autophagy, and slow aging. They discuss how the fasting mimicking diet triggers cellular repair while still providing nourishment.
Learn how nutrient-sensing pathways like mTOR and IGF-1 influence metabolic health and why modern eating habits may accelerate aging. Dr. Hsu explains how short-term fasting can promote healing by tapping into the body’s natural survival mechanisms.
Discover how to apply nourished fasting in your life with the ProLon protocol and why a few cycles a year can significantly improve your healthspan.
In This Episode:
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00:00 Introduction to the Fast Mimicking Diet
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02:49 Interview with Dr. William Hsu: Metabolic Health and Fasting
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04:48 The Science Behind Fasting and Cellular Healing
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06:49 The Evolutionary Perspective on Fasting
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09:22 Understanding Nutrient Sensing Pathways
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14:33 The Nobel Prize-Winning Research on Autophagy
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17:44 The Concept of Fasting Mimicking Diet
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21:25 Exploring the Benefits of Fasting Mimicking Diet
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22:01 The Science Behind Fasting and Systemic Health
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23:22 The Role of Lifestyle Medicine
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24:16 Understanding Digestive Health and Stomach Acid
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26:10 Hormetic Stress and Health Benefits
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27:16 Clinical Research on Fasting Mimicking Diet
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31:32 Practical Application of Fasting Mimicking Diet
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32:43 Personalized Programs for Health Conditions
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35:22 The Future of Lifestyle Medicine
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40:54 Final Thoughts and Call to Action
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"Autophagy is your body’s self-cleaning cycle—and most people never turn it on."
~ Dr. Jockers
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