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Ep. 106: “Innate Lymphocytes” Featuring Dr. Arthur Mortha

The Immunology Podcast

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Insights into Thymic Selection and T Cell Regulation

This chapter delves into the intricate mechanisms of thymic selection, highlighting key signaling pathways that govern T cell survival and diversity. It further examines the effects of negative selection on TCR affinity and the role of cholinergic signaling in shaping T cell responses, particularly concerning autoimmune disease models.

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