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#133 – Manolis Kellis: Biology of Disease
Lex Fridman Podcast
Gene Regulators Are Enriched in Immune Cells
The largest map of the human epigenome that has ever been built across 127 different tissues and samples with dozens of epigenomic marks, measured in hundreds of donors. You basically can map what are the active gene regulatory elements for every one of the tissues in the body. And then we connected these gene regulatory active maps of basically what regions of the human genome are turning on in every one of different tissues. We then can go back and say, where are all of the genetic loci that are associated with disease?
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