Unraveling Inborn Errors of Immunity

This chapter explores the intricate challenges of diagnosing inborn errors of immunity (IEI) by examining over 431 related genes and their clinical presentations. It emphasizes the importance of a thorough clinical history and collaboration between rheumatologists and immunologists to accurately identify underlying immune deficiencies. Through case studies and diagnostic recommendations, the chapter highlights how recognizing atypical symptoms can lead to better patient management and improved outcomes.