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July 2023; papers of the month

The Resus Room

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The Effects of Tranexamic Acid on Neurological Outcomes

The primary outcome they looked at here was favorable neurological outcome at 6 months. For this assessment of whether the patient was high risk they used something called the coast score which ranges from 0 to 7 with one point being assigned for entrapment in a vehicle. Now if that patient who they had concerns about had that coast score of 3 or more they were randomized then to receive either 1 gram of tranexamic acid as a bolus followed by an infusion over 8 hours or saline. So I mean this feels like an important paper to me Simon. What did you think of the findings here? It's interesting isn't it because we are pretty happy with the fact and certainly in the UK that

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