4min chapter

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#133 – Manolis Kellis: Biology of Disease

Lex Fridman Podcast

CHAPTER

The Mendelian Path and the Polygenic Path

The traditional view of biology was you have one postdoc working on this gene. And they'll just figure out everything about that gene, and that's their job. What we've realized is how polygenic the diseases are. So we can't have one post doc protein anymore. We now have to have these cross cutting needs. I'm going to describe the path to circuitry along those needs.

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