Pcos

PCOS is polycystic ovarian syndrome. It's been characterized for quite some time, but we're just learning in the last decade or two that it's much more common than we previously thought. Often you have very low SHBG, which is sex hormone binding globulin. When insulin interacts with the liver, it causes the liver to make less SHBG. So you have a lot of hormone fluctuations called the PCOS rollercoaster.