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Results of Hypertonic Saline or Mannitol Clinical Trial for Treatment of Children with Severe TBI

OPENPediatrics

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Reevaluating Hyperosmolar Therapy in Pediatric TBI

This chapter examines the use of hyperosmolar therapy, particularly hypertonic saline, in treating severe traumatic brain injury in children, contrasting it with traditional mannitol treatments. It discusses recent clinical trial outcomes, highlighting limited effects on intracranial pressure and potential areas for further research.

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