The Evolution of Statins: From Discovery to Impact

This chapter explores the origins and mechanisms behind statins, tracing key research like the Framingham study that linked cholesterol levels to cardiovascular risks. It highlights significant discoveries, including the role of fungi in producing statins and the biochemical pathways involved in cholesterol synthesis. Additionally, the chapter examines the implications of statin use on energy production and muscle health, covering the historical introduction of lovastatin and advancements to newer medications.