The Role of LDL Receptors in Hyper Absorption

Not likely an overproduction issue it's not that your body's making too much cholesterol now that's one lever to look at this is the lever where statins would tend to work if the liver is over producing things you give a medicine to slow down the production then there's a layer in between which is not a direct test for so once the liver pumps out these tennis balls they eventually got a return to the liver. This is the location where the pcsk9 inhibitors work this is where repatha and praline aren't work and then there's an oral one that's being evaluated hopefully to come on the market in the year or two.

Transcript

Play full episode

Transcript

Episode notes

The AI-powered Podcast Player

Save insights by tapping your headphones, chat with episodes, discover the best highlights - and more!

Get the app