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Tranexamic Acid in Critical Care: HALT-IT Trial and Insights
The chapter delves into the use of tranexamic acid (TXA) in critical care, specifically in patients with bleeding conditions, before and after the HALT-IT trial. It explores the study's design, patient population, primary outcomes, and the debate over mortality benefits and concerns about related deaths. The chapter also discusses the inclusion criteria, nuances of the trial design, and implications for various patient groups in critical care settings.