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#038 Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation

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Is Mitoconia a Signal for Mitocondural Biogenesis?

If you're going to make a new mitacondria, then it's going to be young and fresh and not damaged. So we have to make the difference between homeostatic conditions. And for instance, celara differentiation, when cells change their metabolic programs. Or the easiest example is yeast that you suddenly place in a glucos containing medium to allow for the fermentation of glucos in wine or beer production. These yeast cells don't need much oxidenti phosphorlation, and they essentiallreli during the process on glacolysis. They adapt to this change by destroying most of the mitoconia by matophegy. This makes actually ametac metabolic

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