24min chapter

The Peter Attia Drive cover image

#272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D.

The Peter Attia Drive

CHAPTER

Exploring Rapamycin: Dosing, Delivery, and Implications for Aging

This chapter examines the nuanced effects of rapamycin on various tissues, highlighting its complexities in dosing and delivery, particularly related to central nervous system efficacy. The discussion includes the potential for targeted compounds in mTOR inhibition, the implications for neurodegenerative diseases like Alzheimer's, and the promising results from recent studies on dosage impacts in older adults. Key studies and findings are underscored, emphasizing the drug's potential for rejuvenating the immune system and shaping future gerotherapeutics.

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