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Early-Onset Gastrointestinal Cancers

JAMA Clinical Reviews

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Understanding Early-Onset GI Cancers

This chapter examines the concerning rise in early-onset gastrointestinal cancers, particularly focusing on colorectal, pancreatic, and gastroesophageal cancers among individuals under 50. It highlights the interplay of modifiable and non-modifiable risk factors, including obesity and genetic predispositions, while discussing treatment approaches and the psychosocial challenges faced by younger patients. The chapter underscores the need for further research to identify underlying causes and improve patient outcomes in this vulnerable demographic.

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