There are now about a dozen or so excellent studies exploring the use of single or two-session psilocybin treatment in that 25 to 30 milligram range. People were asked about their level of depression relief immediately after, one week after, two weeks after, three weeks after and the degree of relief tended to change over time. In fact, it tended to diminish over time, but it was also stable or remarkably stable, at least by my read,.

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