25min chapter

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Is Water the Dark Matter of Biology? Dr. Michael Hughes, DSPod #237

The DemystifySci Podcast

CHAPTER

Exploring Model Organisms in Biological Research

The chapter discusses the use of yeast as a model organism in studying structural mechanisms in biology, focusing on proteins and diseases like chronic wasting disease. It follows the speaker's journey from undergrad to grad school, where they explore how proteins in yeast with prion domains form stable globules under stress. The discussion also delves into amyloid formation in diseases like Alzheimer's, Parkinson's, and ALS, and the challenges in designing therapies to dissolve these protein fibers.

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