The Stress of Digestion and the Stress of Nutrient Assimilation

Ean i think that's so interesting that it started with this concept of all the cells in your body having a circating rhythm. We think just sort of like the brain and the sleep wake cycle. But it's interesting that you said they can recover from the stress of digestion and the stress of nutrient assimilation. Is there some evidence to support that, like either stress hormones, or inflammatory markers, or something increases in a eating and digestion that led you to think that that was a stress on the body?