This chapter delves into Hunter S. Thompson's unique creative process, emphasizing his coherence amidst extreme moments and the societal impact of 'Fear and Loathing in Las Vegas.' It discusses Thompson's heavy use of amphetamines, the history of these drugs during the 60s and 70s, and their association with influential writing. The chapter also highlights how cocaine and amphetamines shaped the creative processes and lifestyles of artists in the 70s, including Thompson's multi-substance consumption.