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Old/New: HALT-IT and TXA in GI Bleed with cirrhosis

ICU Ed and Todd-Cast

CHAPTER

Trial of Trans-examic Acid in Upper GI Bleeding with Cirrhosis

This chapter focuses on a new trial involving trans-examic acid (TXA) in patients with advanced cirrhosis and hyperfibronolysis, aimed at stabilizing clots in upper gastrointestinal bleeding. Discussions include enrollment criteria for patients with cirrhosis, management strategies like endoscopic therapy, outcomes related to treatment failure and re-bleeding, safety events, and conflicting trial results impacting the administration of TXA in clinical practice.

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