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#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More

The Tim Ferriss Show

CHAPTER

Sirtuins and the Search for Longevity

This chapter explores the role of sirtuins, a group of proteins associated with aging and longevity, and their decreasing activity due to declining NAD levels. It discusses the controversial efficacy of resveratrol in promoting lifespan extension and the scientific skepticism surrounding its benefits. The conversation further delves into the complexities of aging interventions and the need for a proactive approach in healthcare to better address aging-related issues.

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