12min chapter

Immune cover image

Immune 77: Squeezing the most killing out of neutrophils

Immune

CHAPTER

Knox Proteins and Neutrophil Response to Squeezing

The chapter explores the impact of Knox proteins, particularly Knox two and Knox four, on neutrophils passing through small pores and their role in generating reactive oxygen species. It discusses the upregulation of Knox four during neutrophil migration and its crucial role in bacterial killing. The conversation delves into the connection between reactive oxygen species, net formation, and the importance of inducible features in neutrophils.

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