Longevity Diet and FMD

5min Snip

00:00

Play full episode

Summary

Transcript

Episode notes

Fasting mimicking diet can reverse all the problematic effects of a high fat, high calorie diet. The body has a way to then eventually switch you to what's called thrifty mode. And this is actually an old New England general medicine paper. If you push enough to much to much calorie restriction, your body goes into a saving mode and now you're burning less energy. So we tell people, be careful because there's a lot of mechanisms and you need to understand them very well. Otherwise you can have a problem.

Episode #237. Dr Valter Longo introduces intriguing questions to the show: could protein consumption actually be harmful to our health? How important is muscle tissue? Can fasting be used as an adjunct cancer treatment? We investigate these questions and many more, diving into the research on IGF-1, mTOR, and the fasting-mimicking diet.

Specifically, we discuss:

Intro (0:00)
Ideal diets for longevity (2:58)
Important Pathways for aging (9:15)
IGF1 Elevation (16:24)
Actue vs Chronic elevation of IGF1 (19:46)
Danger of Protein Over Consumption (25:11)
Impact of exercise on IGF1 (32:52)
Muscle Mass and Longevity (38:35)
Study on High Protein Later in Life (41:59)
How to get IGF1 tested (48:03)
Low IGF1 & Cognitive Decline (49:54)
Resistance to IGF1 (53:00)
Mendelian Randomization Studies (54:38)
Fasting Mimicking Diet (59:21)
Fasting and Cancer (1:16:03)
Ketogenic Diet & Cancer (1:27:51)
Outro (1:32:15)

To connect with Dr Valter Longo, you can find him on Instagram and Facebook. Learn more about Dr Longo’s research on his website, https://www.valterlongo.com/, where you will also be able to view and purchase his book, The Longevity Diet. Make sure to listen to Dr Longo’s previous appearance on The Proof, Episode #106.

Discover supporting studies and more insights in the full show notes.

Enjoy, friends.

Simon

Want to support the show?

The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.

Simon Hill, MSc, BSc (Hons)

Creator of theproof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

Watch the episodes on YouTube or listen on Apple/Spotify

Connect with me on Instagram, Twitter, and Facebook

Download my complimentary two-week meal plan and high protein Plant Performance recipe book