Are psychedelics effective under anesthesia?: Boris Heifets (Stanford pt 2)
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Effects of Ketamine on Anesthetized Patients with Depression
This chapter discusses a study on the effects of ketamine in treating depression, exploring the role of dissociation in its impact on the subjective experience and clinical outcomes. The study involved administering ketamine or placebo to patients with major depressive disorder during general anesthesia and evaluating depression scores before and after the infusion. The discussion revolves around the unexpected results, the importance of blinding in clinical trials, and the role of expectation and placebo in psychedelic treatments.
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