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Journal Jam 18 The Evidence for TXA – Should Tranexamic Acid Be Routine Therapy in the Bleeding Patient?
Emergency Medicine Cases
The Pitfalls of Subgroup Analysis in Medical Trials
This chapter explores the issue of subgroup analysis in medical trials, emphasizing the need to view subgroups as hypothesis-generating rather than conclusive evidence. It discusses a study by Wallach et al. that found no confirmation of original subgroups showing potential benefit in follow-up trials, highlighting the importance of considering overall trial results.
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Discover
highlights
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