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21min chapter
#92 – Antibiotic Alchemy: Metallo-Beta-Lactamases
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Understanding Metallo Beta-Lactamases
The chapter explores the unique characteristics of metallo beta-lactamases, emphasizing their distinct mechanisms of action and catalytic activity. It discusses the significance of different variants such as NDM, VIM, and IMP in clinical settings, highlighting their abilities to break down specific antibiotics. The conversation also delves into the challenges of developing inhibitors for these enzymes, underscoring the importance of understanding their mechanisms for effective drug development.
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