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Episode 27. Management of PNH
Blood Cancer Talks
The Paradox of P and H
The P and H stem cell produces red blood cells, which does not have CD5 and CD5 and ANCA proteins. The second most common genetic abnormality to come out of a plastic anemia is loss of six P. That's where HLA is about 20, 25% of patients with acquired a Plastic Anemia will have six PLOH. NKG2D makes P&H stem cells less susceptible to the immunologic attack that you have in a plasticAnemia.
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