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Obesogens, Oxidative Stress, Dietary Sugars & Fats, Statins, Diabetes & Causes of Metabolic Dysfunction & Chronic Disease | Robert Lustig | 140

Mind & Matter

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The Impact of Fructose on Obesity and Metabolic Dysfunction

This chapter explores how fructose metabolism differs from glucose, leading to its association with obesity and metabolic diseases like diabetes. It delves into the detailed metabolic pathways in the liver, describing how fructose overwhelms mitochondria, undergoes de novo lipogenesis, and contributes to the formation of fat and elevated triglycerides. The discussion also touches upon the Maillard reaction caused by fructose, its addictive nature, and challenges the traditional calorie theory in weight management.

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