Episode 42 - In The Lab: Rare Groups, Subgroups, Elutes and Fruit Loops | Advanced Blood Banking
Bloody Minded
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Advanced Techniques in Blood Banking
This chapter explores the crucial role of trypsin and DTT in blood banking, especially in relation to RBC surface antigen denaturation and the significance of extended phenotyping prior to daratumumab administration. It provides a comprehensive overview of advanced laboratory techniques, including elution and adsorption, to identify specific antibodies in transfusion scenarios, particularly in complex cases like autoimmune hemolysis. The discussion covers methodologies for conducting direct antiglobulin tests and highlights the practical workflows and challenges faced in blood banks when managing antibody detection and isolation.
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