Exploring the FOLFOX Chemotherapy Regimen and Its Clinical Impact

This chapter explores the FOLFOX chemotherapy regimen, highlighting its role as an adjuvant treatment for colon cancer through the findings of the MOSAIC trial. It reviews the historical development of 5-FU and its combinations, alongside an analysis of clinical trials focusing on the regimen's efficacy and safety for stage 2 and 3 colon cancer patients.