Side effects and safety considerations

Creatine is getting a lot of hype lately, at least according to our listeners.

It’s being pushed for everything from menopause to dementia for its supposed energy-boosting, brain-boosting benefits.

Norman and Tegan explore what is really going on with creatine outside of its muscle-building potential.

References:

• Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? | Journal of the International Society of Sports Nutrition 
• Metabolic Basis of Creatine in Health and Disease: A Bioinformatics-Assisted Review - Nutrients 
• Creatine in Health and Disease 
• Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty and Cachexia
• Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation
• Creatine monohydrate pilot in Alzheimer's: Feasibility, brain creatine, and cognition 
• The Effects of 8-Week Creatine Hydrochloride and Creatine Ethyl Ester Supplementation on Cognition, Clinical Outcomes, and Brain Creatine Levels in Perimenopausal and Menopausal Women (CONCRET-MENOPA): A Randomized Controlled Trial 
• It Is Not Just About Storing Energy: The Multifaceted Role of Creatine Metabolism on Cancer Biology and Immunology
• Creatine Supplementation for Patients with Inflammatory Bowel Diseases: A Scientific Rationale for a Clinical Trial 
• International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine 

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