Exploring Resilience and Robustness in Circadian Clockkeeping

How should we study complex biological networks? How do cells keep time and stay in sync? What does it mean for a network to be resilient?

In this episode, we talk with Rosemary Braun, Associate Professor at Northwestern University in the Department of Molecular Biosciences and a member of the NSF-Simons Center for Quantitative Biology. Rosemary is broadly interested in learning whether “more is different” when it comes to complex molecular networks operating across different temporal and spatial scales. We talk with her about systems approaches to uncovering the “Rules of Life” and about circadian (daily) rhythms. She and her team use machine learning to understand emergent phenomena in networks, with the goal of helping medical professionals target treatments based on an individual patient’s circadian rhythm.

Cover art: Keating Shahmehri. Find a transcript of this episode on our website.