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75. PK: Blethering about Bioavailability

ID:IOTS - Infectious Disease Insight Of Two Specialists

CHAPTER

Drug Absorption in the Gastrointestinal Tract

Exploring the differences in oral drug absorption between the stomach and the small intestine, highlighting the impact of surface area, transit time, and acidity on drug absorption. Delving into drug ionization and its influence on drug uptake, along with the role of solute carrier transporters like oat and OCT in facilitating drug absorption. The chapter also covers methods of drug transport, including passive diffusion, active transport, and first pass metabolism in the liver.

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