Utilizing Reduced-Dose Systemic Peripheral Fibrinolysis in High-Risk Submassive Patients

The chapter explores the use of a reduced-dose systemic peripheral fibrinolysis intervention in patients with massive pulmonary embolism not in critical condition. It discusses the protocol, outcomes, safety considerations, and implications for high-risk submassive patients. The debate on optimal dosing strategies, patient responses, and challenges in implementing alternative TPA dosing protocols is also highlighted.