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Autophagy: Understanding the Process of Cellular Breakdown
In this chapter, the hosts delve into the concept of autophagy and mitophagy, debunking misconceptions around them. They explain the mechanisms of protein degradation, particularly macroautophagy, comparing it to decluttering a room and a whale feasting on krill. The chapter highlights the benefits and complexities of autophagy, including its potential exploitation by cancer cells and a study on enhancing chemotherapy effectiveness through autophagy inhibition.