Conservative Oxygenation in Ventilated Emergency Admissions

The chapter discusses the findings of a study on conservative oxygenation in ventilated emergency admissions. They explain that the length of organ support, specifically ventilation, is a dominant factor. There is a small difference in the duration of ventilation between the conservative and liberal groups, resulting in a significant overall result when combined with mortality. The length of stay among survivors is also affected, with the intervention group showing a numerically lower effect. Functional status and healthcare cost show no significant difference between the two groups. Subgroup analysis suggests no variation based on age or baseline hemoglobin, but there is a hint of potential variation based on baseline heart rate. The chapter concludes that conservative oxygenation has a small but significant benefit on organ failure duration and severity, with supportive secondary outcomes. The authors recommend it as a starting point for ventilated emergency admissions.