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Immune 64: A tangled web of wires

Immune

CHAPTER

Enhanced Immune Response and Vaccination Strategies

The chapter explores the impact of SARS-CoV-2 exposure on T cell and IgG responses in individuals with varied vaccination and infection histories, highlighting the consistent high T cell responses and increasing antibody responses with multiple exposures. It discusses the significance of T cell protection against severe disease, the potential benefits of booster shots, and a multi-tiered approach to enhance immunity. The concept of 'hybrid immunity' from combining infection and vaccination is introduced, along with insights into RSV human challenge trials and the importance of innate immunity in controlling initial viral infections.

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