The Risk of Infection After CAR-T

The risk of infection varies depending on whether someone had a B-cell lymphoma versus multiple myeloma where you might have more plasma cells problems. Other factors that enter into play include baseline cytopenias, other medical comorbidities, and if they have previous infections. Early complications of CAR-T to be taken into consideration are cytopenia release syndrome or CRS, immune effector cell associated neurotoxacety syndrome or ICANS,. hemophagocytic lymphoistiosylicis or HHH, the famous one, and macrophage activation syndrome or MAS. Those with active C&V disease, those with ICans requiring anti-IL6