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FIRST-ABC (step up) Trial Result Presentation

Critical Care Reviews Podcast

CHAPTER

The Role of Primary Analysis in Non-Inferiority in Respiratory Sports

We had 24 participating pediatric intensive care and high dependency units, so collectively critical care units across England, Scotland and Wales that participated in the trial. And also, we had a per protocol population, so it gave us an opportunity to have slightly inflated sample size for non-adherence in the per protocol population. There's also subgroup analysis for age, comorbidities, reason for admission, SF ratio, severity of respiratory distress and also the restate of non-invasive respiratory sports at randomization. I'm going to pass back to Ram now to take you through the results. Thank you.

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