The Role of the Liver in Metabolic Health

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The liver is the first main organ that when we eat food, the nutrients go into the liver. And this is the place where a lot of the processing of protein and fats is occurring. If you block fructose metabolism in the liver, you get benefits above and beyond the liver. You get, you end up regulating your intake, food intake and maybe that has a role in preventing fat and weight gain. It may not be the only site. We know that there are things going on and other tissues, but it's like the king. Right.

Episode #233. Dive deeper into how saturated fats and sugar affect metabolism and the liver in this conversation with Dr Richard Johnson. The Proof community had many questions after Dr Johnson’s appearance on Episode #215, and we return today to answer them: What does human outcome data say? What are the risks of the keto diet and high blood sugar? Do our opinions align?

We answer these questions and more, addressing:

Intro (0:00)
Dr. Johnson’s Thesis on Fructose (3:27)
Gaps in Current Studies (11:28)
Saturated Fat Versus Sugar (20:20)
Long-term risk of Keto Diet (33:09)
Fructose Effect on Saturated Fat (36:28)
Survival Mechanisms (40:40)
Type of Fat (46:37)
Metabolic Health & Fructose (53:00)
Role of the Liver (1:02:20)
Problem with High Blood Sugar (1:09:15)
Triglycerides & Uric Acid (1:17:22)
When Fatty Liver Happens (1:27:52)
Ceramides (1:31:45)
Outro (1:33:30)

To connect with Dr Richard Johnson, you can find him on Instagram and Twitter, or learn more on his website. For a more comprehensive picture of Dr Johnson’s stance, make sure to check out his book, Nature Wants Us To Be Fat.

Discover additional resources, supporting studies, and more insights in the full show notes.

Enjoy, friends.

Simon

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Simon Hill, Msc, Bsc (Hons)

Creator of TheProof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

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