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FIRST-ABC (step up) Trial Result Presentation

Critical Care Reviews Podcast

CHAPTER

The Effect of Randomization on Mortality at PQ Discharge

High flow compared to CPAP met the criterion for non-inferiority, as we pre-specified. The direction of effect that we saw was quite consistent in all these analyses and populations. Adverse events were noted in about 6% of patients on the HINDHAIFLO group and 11% of patients in the CPAP group. And the biggest difference came in the incidence of nasal trauma or nasal pressure areas from this use of CPAP.

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