This chapter delves into the twin-cycle hypothesis, explaining how excess food intake leads to fat accumulation in the liver and the subsequent vicious cycle of insulin resistance and increased fat production. It discusses the connection between type 2 diabetes, obesity, and the accumulation of fat in various tissues, highlighting the importance of adopting a hypocaloric diet for managing the condition. The chapter also explores the impact of weight loss on reversing fat levels in the liver and improving beta cell function.

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