Navigating Health and Discomfort in Times of Crisis

What if the key to living longer isn’t avoiding stress—but mastering it 

Jeff Krasno, founder of Commune and renowned stress expert, joins Dave to reveal why most of us have stress all wrong. In this fascinating conversation, Jeff redefines how we think about stress—showing how it can be your greatest ally instead of your worst enemy. From his groundbreaking new book Good Stress to the ancient practices that have stood the test of time, Jeff shares how to unlock the hidden potential of stress to build resilience, foster connections, and boost longevity. 

You’ll discover why crying is an emotional biohack, how to spot the fine line between good and bad stress, and why the modern world keeps us stuck in a chronic stress loop—and how to break free. Jeff also dives into the science of emotional regulation, the role of connection in health, and the radical power of embracing discomfort to create balance and ease in your life. 

What You’ll Learn: 

• How to turn stress into a tool for resilience and longevity 

• Why Jeff calls chronic ease the root of modern disease 

• The science of tears: how crying regulates stress and boosts health 

• How you can build a “psychological immune system” for emotional regulation 

• The key to balancing good stress and avoiding burnout 

• Why discomfort is the path to growth—and how to embrace it 

Resources:  

• 2025 Biohacking Conference: https://biohackingconference.com/2025 

• Jeff Krasno’s Website – https://www.jeffkrasno.com/ 

• Preorder Good Stress – https://www.onecommune.com/goodstressbook#preorder 

• Follow Jeff on Instagram – https://www.instagram.com/jeffkrasno 

• Danger Coffee: https://dangercoffee.com 

• Dave Asprey’s Website: https://daveasprey.com 

• Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books 

• Dave Asprey’s Linktree: https://linktr.ee/daveasprey 

• Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com 

• Own an Upgrade Labs: https://ownanupgradelabs.com 

• Upgrade Labs: https://upgradelabs.com 

• 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com 

SPONSORS:  

• Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. 

• Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. 

Timestamps: 

• 00:00 – Intro 

• 01:02 – Meet Jeff Krasno 

• 02:16 – Topanga Fires Survival 

• 04:14 – Good Stress vs. Bad Stress 

• 06:14 – Cortisol’s Role in Stress 

• 13:13 – Social Media Triggers 

• 20:32 – Stressful Conversations 

• 31:34 – Cold Therapy Benefits 

• 42:26 – Stress and Recovery Balance 

• 45:58 – High Altitude Training 

• 47:29 – Cold Therapy Fails 

• 49:42 – Science of Crying 

• 54:51 – Reflections on Legacy 

• 59:37 – Balancing Stress and Ease 

• 01:10:30 – Nature and Spirituality 

• 01:22:52 – Facing Death with Grace 

• 01:32:53 – Closing Thoughts 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.