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The Role of Body Fat in Hypertrophy
When you're assessing P ratios, it's just lean mass as a percentage of total mass. In those studies on anorexic people, we don't actually know the degree to which the lean mass they gained contributing to that really high P ratio was regaining skeletal muscle mass. It is theoretically possible that at sufficiently high levels of inflammation, sufficiently low levels of insulin sensitivity, that those things could have a negative impact on hypertrophy. That is certainly possible.