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101 - Automatic ABO

The Curious Clinicians

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Antibody Production and Evolutionary Immunity

This chapter explores how individuals produce antibodies against blood types without prior exposure, emphasizing the influence of gut microbes and diet. It discusses the evolutionary significance of anti-ABO antibodies, including their development in germ-free environments and the possible implications of early life exposures. The conversation also touches on the complexities of immunity, autoimmunity, and the parallels between human antibodies and pathogens.

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