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#247 SPEP It Up: MGUS, Myeloma, and Immunology, Oh My!

The Curbsiders Internal Medicine Podcast

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Distinguishing Between Benign and Malignant Monoclonal Processes

This chapter explores the process of differentiating between benign and malignant monoclonal processes in patients presenting with an M spike. It discusses the prevalence of a benign condition called monoclonal gamopathy, the importance of additional testing such as bone marrow biopsy, and the criteria for referring a patient to a hematologist. Asymptomatic myeloma and Waldenstrom's macroglobulinemia are also explained.

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