The Role of Prophylaxis in Cancer Treatment

For bacterial infection the common strategy would be fluoroquinolone prophylaxis, usually with levofloxacin during the time of neutropenia. For HSV and VZV there's a broad consensus to the acyclovir or valesicylovir from initiation of lymphotic lesion and up until one year after CAR T. The most recent iteration of the NCCN guidelines for prevention and treatment of cancer related infections was published in October 2022.