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216. Should you worry about high cholesterol? With Aseem Malhotra

Paul Saladino MD podcast

CHAPTER

Mendelian Randomizations in GWAS Studies

Paul Waldman: I just want to highlight what you said there because it's so important, and this is fairly technical. You talked about these Mendelian randomizations, which are abbreviated MR, and similar to that, are genome-wide association studies called GWAS. And those are the evidence put forth by people who are preaching that APOB is a direct driver of cardiovascular disease. He says we need to treat the whole patient, not a biomarker; medicine shouldn't be an exact fine. Waldman: We should give patients numbers in a way that they can understand their hopes and anxieties without coercion.

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