Mast cells, when highly activated, can be triggered by seemingly harmless substances like water, leading to a mast cell activation process. The susceptibility to mast cell activation is not related to food allergies but rather on how reactive the cells are in response to environmental factors. Recent knowledge on mast cell activation has expanded, with a higher prevalence than previously believed, affecting 15-20% of the population. The book 'Never Against Occam's Razor' by Dr. Afrin sheds light on this condition, which was previously misunderstood and thought to be rare.

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